Author Info: (1) Department of Bioengineering, Imperial College London, London, UK. (2) Human Biology Division, Fred Hutchinson Cancer Center, Seattle, WA, USA. Division of Hematology/Oncology,

Author Info: (1) Department of Bioengineering, Imperial College London, London, UK. (2) Human Biology Division, Fred Hutchinson Cancer Center, Seattle, WA, USA. Division of Hematology/Oncology, Department of Medicine, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA. (3) Translational Science and Therapeutics Division, Fred Hutchinson Cancer Center, Seattle, WA, USA. (4) Translational Science and Therapeutics Division, Fred Hutchinson Cancer Center, Seattle, WA, USA. (5) Department of Bioengineering, Imperial College London, London, UK. (6) Department of Bioengineering, Imperial College London, London, UK. (7) Department of Bioengineering, Imperial College London, London, UK. (8) Department of Bioengineering, Imperial College London, London, UK. (9) Department of Bioengineering, Imperial College London, London, UK. (10) Department of Microbiology, Immunology and Molecular Genetics, UCLA, Duarte, CA, USA. (11) Department of Bioengineering, Imperial College London, London, UK. (12) Department of Bioengineering, Imperial College London, London, UK. (13) Department of Bioengineering, Imperial College London, London, UK. (14) Department of Bioengineering, Imperial College London, London, UK. (15) Division of Hematology/Oncology, Department of Medicine, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA. (16) Human Biology Division, Fred Hutchinson Cancer Center, Seattle, WA, USA. Division of Hematology/Oncology, Department of Medicine, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA. (17) Department of Hematology and Hematopoietic Cell Transplantation, City of Hope, Duarte, CA, USA. Department of Immuno-Oncology, Beckman Research Institute of City of Hope, Duarte, CA, USA. (18) Translational Science and Therapeutics Division, Fred Hutchinson Cancer Center, Seattle, WA, USA. Division of Medical Oncology, University of Washington, Seattle, WA, USA. (19) Human Biology Division, Fred Hutchinson Cancer Center, Seattle, WA, USA. jklee@mednet.ucla.edu. Division of Hematology/Oncology, Department of Medicine, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA. jklee@mednet.ucla.edu. Parker Institute for Cancer Immunotherapy at UCLA, Los Angeles, CA, USA. jklee@mednet.ucla.edu. (20) Department of Bioengineering, Imperial College London, London, UK. j.ishihara@imperial.ac.uk. Exploratory Oncology Research and Clinical Trial Center (EPOC), National Cancer Center, Chiba, Japan. j.ishihara@imperial.ac.uk.

Author Info: (1) Department of Pediatric Oncology, Dana-Farber Cancer Institute, Boston, MA, USA. (2) Department of Genetics, Stanford University, Stanford, CA, USA. Department of Medicine, Sta

Author Info: (1) Department of Pediatric Oncology, Dana-Farber Cancer Institute, Boston, MA, USA. (2) Department of Genetics, Stanford University, Stanford, CA, USA. Department of Medicine, Stanford University School of Medicine, Stanford, CA, USA. (3) Computational and Systems Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA. (4) Department of Medicine, Stanford University School of Medicine, Stanford, CA, USA. (5) Proteas Health, Torrance, CA, USA. (6) Department of Pediatric Oncology, Dana-Farber Cancer Institute, Boston, MA, USA. (7) Department of Pathology, Stanford University, Stanford, CA, USA. (8) Department of Pediatric Oncology, Dana-Farber Cancer Institute, Boston, MA, USA. (9) Department of Pediatric Oncology, Dana-Farber Cancer Institute, Boston, MA, USA. (10) Department of Pediatric Oncology, Dana-Farber Cancer Institute, Boston, MA, USA. (11) Department of Radiation Oncology and Stanford Cancer Institute, Stanford University School of Medicine, Stanford, CA, USA. (12) Department of Pediatric Oncology, Dana-Farber Cancer Institute, Boston, MA, USA. (13) Immunology Graduate Program, Stanford University School of Medicine, Stanford, CA, USA. Center for Cancer Cell Therapy, Stanford Cancer Institute, Stanford University School of Medicine, Stanford, CA, USA. (14) Department of Medicine, Stanford University School of Medicine, Stanford, CA, USA. (15) Immuno-Oncology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA. (16) Immuno-Oncology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA. Parker Institute for Cancer Immunotherapy, San Francisco, CA, USA. (17) Department of Pathology, Stanford University, Stanford, CA, USA. Parker Institute for Cancer Immunotherapy, San Francisco, CA, USA. (18) Department of Pediatrics, City of Hope National Medical Center, Duarte, CA, USA. Department of Immuno-oncology, City of Hope National Medical Center, Duarte, CA, USA. (19) Computational and Systems Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA. (20) Department of Pediatric Oncology, Dana-Farber Cancer Institute, Boston, MA, USA. robbie_majzner@dfci.harvard.edu. Parker Institute for Cancer Immunotherapy, San Francisco, CA, USA. robbie_majzner@dfci.harvard.edu. Division of Hematology/Oncology, Boston Children's Hospital, Boston, MA, USA. robbie_majzner@dfci.harvard.edu. Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA. robbie_majzner@dfci.harvard.edu.

Author Info: (1) Department of Gastrointestinal Oncology, Netherlands Cancer Institute, Amsterdam, the Netherlands. (2) Department of Gastrointestinal Oncology, Netherlands Cancer Institute, Am

Author Info: (1) Department of Gastrointestinal Oncology, Netherlands Cancer Institute, Amsterdam, the Netherlands. (2) Department of Gastrointestinal Oncology, Netherlands Cancer Institute, Amsterdam, the Netherlands. (3) Department of Pathology, Netherlands Cancer Institute, Amsterdam, the Netherlands. (4) Department of Biometrics, Netherlands Cancer Institute, Amsterdam, the Netherlands. (5) Department of Surgery, Netherlands Cancer Institute, Amsterdam, the Netherlands. (6) Department of Pathology, Leiden University Medical Center, Leiden, the Netherlands. (7) Department of Molecular Carcinogenesis, Netherlands Cancer Institute, Amsterdam, the Netherlands. (8) Natera, Inc, Austin, TX, USA. (9) Natera, Inc, Austin, TX, USA. (10) Department of Molecular Oncology and Immunology, Netherlands Cancer Institute, Amsterdam, the Netherlands. (11) Department of Gastrointestinal Oncology, Netherlands Cancer Institute, Amsterdam, the Netherlands. Department of Gastroenterology and Hepatology, Leiden University Medical Center, Leiden, the Netherlands. (12) Department of Molecular Oncology and Immunology, Netherlands Cancer Institute, Amsterdam, the Netherlands. Department of Medical Oncology, Netherlands Cancer Institute, Amsterdam, the Netherlands. (13) Department of Molecular Oncology and Immunology, Netherlands Cancer Institute, Amsterdam, the Netherlands. Oncode Institute, Utrecht, the Netherlands. (14) Department of Pathology, Leiden University Medical Center, Leiden, the Netherlands. (15) Department of Molecular Oncology and Immunology, Netherlands Cancer Institute, Amsterdam, the Netherlands. Oncode Institute, Utrecht, the Netherlands. Department of Hematology, Leiden University Medical Center, Leiden, the Netherlands. (16) Department of Molecular Carcinogenesis, Netherlands Cancer Institute, Amsterdam, the Netherlands. Oncode Institute, Utrecht, the Netherlands. (17) Department of Gastrointestinal Oncology, Netherlands Cancer Institute, Amsterdam, the Netherlands. m.chalabi@nki.nl. Department of Medical Oncology, Netherlands Cancer Institute, Amsterdam, the Netherlands. m.chalabi@nki.nl.

Author Info: (1) Department of Radiation Oncology, Division of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA. agrippin@mdanderson.org. (2) Lillian S. W

Author Info: (1) Department of Radiation Oncology, Division of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA. agrippin@mdanderson.org. (2) Lillian S. Wells Department of Neurosurgery, Preston A. Wells, Jr. Center for Brain Tumor Therapy, McKnight Brain Institute, University of Florida, Gainesville, FL, USA. (3) McGovern Medical School, Houston, TX, USA. (4) Department of Radiation Oncology, Division of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA. (5) Department of Radiation Oncology, Division of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA. (6) Department of Radiation Oncology, Division of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA. (7) Department of Enterprise Data Engineering and Analytics, The University of Texas MD Anderson Cancer Center, Houston, TX, USA. (8) Department of Radiation Oncology, Division of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA. (9) Department of Radiation Oncology, Division of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA. (10) Department of Radiation Oncology, Division of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA. (11) Department of Neurosurgery, The University of Texas MD Anderson Cancer Center, Houston, TX, USA. Brain Tumor Center, The University of Texas MD Anderson Cancer Center, Houston, TX, USA. (12) Lillian S. Wells Department of Neurosurgery, Preston A. Wells, Jr. Center for Brain Tumor Therapy, McKnight Brain Institute, University of Florida, Gainesville, FL, USA. (13) Lillian S. Wells Department of Neurosurgery, Preston A. Wells, Jr. Center for Brain Tumor Therapy, McKnight Brain Institute, University of Florida, Gainesville, FL, USA. (14) Lillian S. Wells Department of Neurosurgery, Preston A. Wells, Jr. Center for Brain Tumor Therapy, McKnight Brain Institute, University of Florida, Gainesville, FL, USA. (15) Lillian S. Wells Department of Neurosurgery, Preston A. Wells, Jr. Center for Brain Tumor Therapy, McKnight Brain Institute, University of Florida, Gainesville, FL, USA. (16) McGovern Medical School, Houston, TX, USA. (17) Lillian S. Wells Department of Neurosurgery, Preston A. Wells, Jr. Center for Brain Tumor Therapy, McKnight Brain Institute, University of Florida, Gainesville, FL, USA. (18) Lillian S. Wells Department of Neurosurgery, Preston A. Wells, Jr. Center for Brain Tumor Therapy, McKnight Brain Institute, University of Florida, Gainesville, FL, USA. (19) Lillian S. Wells Department of Neurosurgery, Preston A. Wells, Jr. Center for Brain Tumor Therapy, McKnight Brain Institute, University of Florida, Gainesville, FL, USA. Department of Pediatrics, Division of Hematology-Oncology, University of Florida, Gainesville, FL, USA. (20) Department of Dermatology, Baylor College of Medicine, Houston, TX, USA. (21) Department of Radiation Oncology, Division of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA. (22) Department of Radiation Oncology, Division of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA. (23) Department of Radiation Oncology, Division of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA. (24) Department of Radiation Oncology, Division of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA. (25) Department of Radiation Oncology, Division of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA. (26) Department of Radiation Oncology, Division of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA. (27) Department of Pathology, Stanford University, Stanford, CA, USA. (28) McGovern Medical School, Houston, TX, USA. (29) McGovern Medical School, Houston, TX, USA. (30) Department of Thoracic Imaging, The University of Texas MD Anderson Cancer Center, Houston, TX, USA. (31) Scripps Health, San Diego, CA, USA. (32) Department of Radiation Oncology, Division of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA. (33) Department of Radiation Oncology, Division of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA. (34) Lillian S. Wells Department of Neurosurgery, Preston A. Wells, Jr. Center for Brain Tumor Therapy, McKnight Brain Institute, University of Florida, Gainesville, FL, USA. (35) Lillian S. Wells Department of Neurosurgery, Preston A. Wells, Jr. Center for Brain Tumor Therapy, McKnight Brain Institute, University of Florida, Gainesville, FL, USA. (36) Department of Radiation Oncology, Division of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA. (37) University of North Carolina, Chapel Hill, NC, USA. (38) Department of Radiation Oncology, Division of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA. (39) Department of Surgical Oncology, Division Surgery, The University of Texas MD Anderson Cancer Center, Houston, TX, USA. (40) Department of Surgical Oncology, Division Surgery, The University of Texas MD Anderson Cancer Center, Houston, TX, USA. (41) Department of Radiation Oncology, Division of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA. (42) Department of Radiation Oncology, Division of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA. (43) Department of Thoracic/Head & Neck Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA. (44) Department of Thoracic/Head & Neck Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA. (45) Department of Thoracic/Head & Neck Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA. (46) Department of Thoracic and Cardiovascular Surgery, The University of Texas MD Anderson Cancer Center, Houston, TX, USA. (47) Department of Genitourinary Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA. (48) Department of Biostatistics, The University of Texas MD Anderson Cancer Center, Houston, TX, USA. (49) Department of Biostatistics, The University of Florida, Gainesville, FL, USA. (50) Department of Biostatistics, The University of Texas MD Anderson Cancer Center, Houston, TX, USA. (51) Department of Genitourinary Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA. Department of Immunology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA. James P. Allison Institute, The University of Texas MD Anderson Cancer Center, Houston, TX, USA. (52) Department of Thoracic/Head & Neck Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA. (53) Department of Thoracic/Head & Neck Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA. (54) Department of Thoracic/Head & Neck Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA. (55) Department of Surgical Oncology, Division Surgery, The University of Texas MD Anderson Cancer Center, Houston, TX, USA. (56) Department of Neurosurgery, The University of Texas MD Anderson Cancer Center, Houston, TX, USA. Brain Tumor Center, The University of Texas MD Anderson Cancer Center, Houston, TX, USA. (57) Department of Thoracic/Head & Neck Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA. (58) Lillian S. Wells Department of Neurosurgery, Preston A. Wells, Jr. Center for Brain Tumor Therapy, McKnight Brain Institute, University of Florida, Gainesville, FL, USA. (59) Department of Radiation Oncology, Division of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA. (60) Lillian S. Wells Department of Neurosurgery, Preston A. Wells, Jr. Center for Brain Tumor Therapy, McKnight Brain Institute, University of Florida, Gainesville, FL, USA. elias.sayour@neurosurgery.ufl.edu. Department of Pediatrics, Division of Hematology-Oncology, University of Florida, Gainesville, FL, USA. elias.sayour@neurosurgery.ufl.edu. (61) Department of Radiation Oncology, Division of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA. shlin@mdanderson.org.

Author Info: (1) Medical Research Council Toxicology Unit, University of Cambridge, Gleeson Building, Tennis Court Road, Cambridge, CB2 1QR, UK. munetomo.takahashi@gmail.com. Department of Prev

Author Info: (1) Medical Research Council Toxicology Unit, University of Cambridge, Gleeson Building, Tennis Court Road, Cambridge, CB2 1QR, UK. munetomo.takahashi@gmail.com. Department of Preventive Medicine, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan. munetomo.takahashi@gmail.com. (2) Division of Molecular Regulation of Inflammatory and Immune Diseases, Research Institute for Biomedical Sciences, Tokyo University of Science, Chiba, Japan. (3) Department of Preventive Medicine, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan. Division of Molecular Regulation of Inflammatory and Immune Diseases, Research Institute for Biomedical Sciences, Tokyo University of Science, Chiba, Japan. Department of Host-Microbe Interactions, St. Jude Children's Research Hospital, Memphis, TN, USA. (4) Division of Molecular Regulation of Inflammatory and Immune Diseases, Research Institute for Biomedical Sciences, Tokyo University of Science, Chiba, Japan. (5) Division of Molecular Regulation of Inflammatory and Immune Diseases, Research Institute for Biomedical Sciences, Tokyo University of Science, Chiba, Japan. (6) Division of Molecular Regulation of Inflammatory and Immune Diseases, Research Institute for Biomedical Sciences, Tokyo University of Science, Chiba, Japan. (7) Department of Immunology and Immunotherapy, School of Infection, Inflammation and Immunology, College of Medicine and Health, University of Birmingham, Birmingham, B15 2TT, UK. (8) Department of Preventive Medicine, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan. (9) Medical Research Council Toxicology Unit, University of Cambridge, Gleeson Building, Tennis Court Road, Cambridge, CB2 1QR, UK. (10) Division of Molecular Regulation of Inflammatory and Immune Diseases, Research Institute for Biomedical Sciences, Tokyo University of Science, Chiba, Japan. (11) Division of Molecular Regulation of Inflammatory and Immune Diseases, Research Institute for Biomedical Sciences, Tokyo University of Science, Chiba, Japan. ueha@rs.tus.ac.jp.

Author Info: (1) State Key Laboratory of Immune Response and Immunotherapy, Institute of Immunology, School of Basic Medical Sciences, Division of Life Sciences and Medicine, University of Scie

Author Info: (1) State Key Laboratory of Immune Response and Immunotherapy, Institute of Immunology, School of Basic Medical Sciences, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, China. (2) MOE Key Laboratory for Cellular Dynamics, School of Life Sciences, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, China. (3) State Key Laboratory of Immune Response and Immunotherapy, Institute of Immunology, School of Basic Medical Sciences, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, China. (4) State Key Laboratory of Immune Response and Immunotherapy, Institute of Immunology, School of Basic Medical Sciences, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, China. (5) State Key Laboratory of Immune Response and Immunotherapy, Institute of Immunology, School of Basic Medical Sciences, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, China. (6) State Key Laboratory of Immune Response and Immunotherapy, Institute of Immunology, School of Basic Medical Sciences, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, China. (7) State Key Laboratory of Immune Response and Immunotherapy, Institute of Immunology, School of Basic Medical Sciences, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, China. (8) Hongqiao International Institute of Medicine, Tongren Hospital & Shanghai Institute of Immunology, State Key Laboratory of Systems Medicine for Cancer, Shanghai Jiao Tong University School of Medicine, Shanghai, China. (9) State Key Laboratory of Immune Response and Immunotherapy, Institute of Immunology, School of Basic Medical Sciences, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, China. Hefei TG ImmunoPharma Corporation Limited, Hefei, China. (10) State Key Laboratory of Immune Response and Immunotherapy, Institute of Immunology, School of Basic Medical Sciences, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, China. mahongdi@ustc.edu.cn. (11) Hefei TG ImmunoPharma Corporation Limited, Hefei, China. haoyusun@ustc.edu.cn. Department of Immunology, School of Basic Medical Sciences, Fudan University, Shanghai, China. haoyusun@ustc.edu.cn. Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, China. haoyusun@ustc.edu.cn. Department of Medical Oncology, Fudan University Shanghai Cancer Center, Shanghai, China. haoyusun@ustc.edu.cn. (12) State Key Laboratory of Immune Response and Immunotherapy, Institute of Immunology, School of Basic Medical Sciences, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, China. tzg@ustc.edu.cn. Hefei TG ImmunoPharma Corporation Limited, Hefei, China. tzg@ustc.edu.cn. Key Laboratory of Quantitative Synthetic Biology, Shenzhen Institute of Synthetic Biology, Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences, Shenzhen, China. tzg@ustc.edu.cn. (13) State Key Laboratory of Immune Response and Immunotherapy, Institute of Immunology, School of Basic Medical Sciences, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, China. ustczxh@ustc.edu.cn. Hefei TG ImmunoPharma Corporation Limited, Hefei, China. ustczxh@ustc.edu.cn. Key Laboratory of Quantitative Synthetic Biology, Shenzhen Institute of Synthetic Biology, Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences, Shenzhen, China. ustczxh@ustc.edu.cn.

Author Info: (1) Goethe University, University Hospital, Institute of Neurology (Edinger Institute), Frankfurt, Germany; Frankfurt Cancer Institute (FCI), Frankfurt, Germany. (2) Goethe Univers

Author Info: (1) Goethe University, University Hospital, Institute of Neurology (Edinger Institute), Frankfurt, Germany; Frankfurt Cancer Institute (FCI), Frankfurt, Germany. (2) Goethe University, University Hospital, Institute of Neurology (Edinger Institute), Frankfurt, Germany; Frankfurt Cancer Institute (FCI), Frankfurt, Germany. (3) Goethe University, University Hospital, Institute of Neurology (Edinger Institute), Frankfurt, Germany; Frankfurt Cancer Institute (FCI), Frankfurt, Germany; University Cancer Center (UCT), Frankfurt, Germany. (4) Goethe University, University Hospital, Institute of Neurology (Edinger Institute), Frankfurt, Germany; Frankfurt Cancer Institute (FCI), Frankfurt, Germany. (5) Goethe University, University Hospital, Institute of Neurology (Edinger Institute), Frankfurt, Germany; Frankfurt Cancer Institute (FCI), Frankfurt, Germany. (6) Goethe University, University Hospital, Institute of Neurology (Edinger Institute), Frankfurt, Germany; Frankfurt Cancer Institute (FCI), Frankfurt, Germany; University Cancer Center (UCT), Frankfurt, Germany. (7) Goethe University, University Hospital, Institute of Neurology (Edinger Institute), Frankfurt, Germany; Frankfurt Cancer Institute (FCI), Frankfurt, Germany; University Cancer Center (UCT), Frankfurt, Germany. (8) Goethe University, University Hospital, Institute of Neurology (Edinger Institute), Frankfurt, Germany; Frankfurt Cancer Institute (FCI), Frankfurt, Germany. (9) Goethe University, University Hospital, Institute of Neurology (Edinger Institute), Frankfurt, Germany. (10) Frankfurt Cancer Institute (FCI), Frankfurt, Germany; University Cancer Center (UCT), Frankfurt, Germany; Goethe University, University Hospital, Dr. Senckenberg Institute of Neurooncology, Frankfurt, Germany. (11) University Cancer Center (UCT), Frankfurt, Germany; Goethe University, University Hospital, Institute of Neuroradiology, Frankfurt, Germany; German Cancer Consortium (DKTK), Partner Site Frankfurt/Mainz and German Cancer Research Center (DKFZ), Heidelberg, Germany. (12) Goethe University, University Hospital, Institute of Neurology (Edinger Institute), Frankfurt, Germany; Frankfurt Cancer Institute (FCI), Frankfurt, Germany; University Cancer Center (UCT), Frankfurt, Germany. (13) Frankfurt Cancer Institute (FCI), Frankfurt, Germany; University Cancer Center (UCT), Frankfurt, Germany; Goethe University, University Hospital, Institute of Neuroradiology, Frankfurt, Germany; German Cancer Consortium (DKTK), Partner Site Frankfurt/Mainz and German Cancer Research Center (DKFZ), Heidelberg, Germany. (14) Goethe University, University Hospital, Institute of Neurology (Edinger Institute), Frankfurt, Germany; Frankfurt Cancer Institute (FCI), Frankfurt, Germany; University Cancer Center (UCT), Frankfurt, Germany; German Cancer Consortium (DKTK), Partner Site Frankfurt/Mainz and German Cancer Research Center (DKFZ), Heidelberg, Germany. (15) Goethe University, University Hospital, Institute of Neurology (Edinger Institute), Frankfurt, Germany; Frankfurt Cancer Institute (FCI), Frankfurt, Germany; German Cancer Consortium (DKTK), Partner Site Frankfurt/Mainz and German Cancer Research Center (DKFZ), Heidelberg, Germany. (16) Goethe University, University Hospital, Institute of Neurology (Edinger Institute), Frankfurt, Germany; Frankfurt Cancer Institute (FCI), Frankfurt, Germany; University Cancer Center (UCT), Frankfurt, Germany. Electronic address: imkeller@rz.uni-frankfurt.de.

Author Info: (1) Institut Gustave Roussy, Villejuif, France. (2) INSERM, EFS BFC, UMR1098-RIGHT, University of Franche-Comte, Besançon, France, Besançon, Bourgogne-Franche-Comte, France. (3) Un

Author Info: (1) Institut Gustave Roussy, Villejuif, France. (2) INSERM, EFS BFC, UMR1098-RIGHT, University of Franche-Comte, Besançon, France, Besançon, Bourgogne-Franche-Comte, France. (3) Université Bourgogne Franche-Comté, EFS, INSERM, UMR RIGHT, F-25000 Besançon, France, Besançon, France. (4) Université Bourgogne Franche-Comté, France. (5) Université Bourgogne Franche-Comté, EFS, INSERM, UMR RIGHT, F-25000 Besançon, France, Besançon, France. (6) Université de Franche-Comté, EFS, INSERM, UMR RIGHT, F-25000 Besançon, France, Besançon, France. (7) Université Marie et Louis Pasteur, EFS, INSERM UMR1098 RIGHT, Besançon, F-25000, France, Besançon, Bourgogne-Franche-Comte, France. (8) Université Bourgogne Franche-Comté, France. (9) University of Lausanne, Lausanne, Switzerland. (10) Interactions Hte-Greffon-Tumeur & Ingénierie Cellulaire et Génique, Besançon, France. (11) Memorial Sloan Kettering Cancer Center, France. (12) Université de Franche-Comté, EFS, INSERM, UMR RIGHT, F-25000 Besançon, France, Besançon, France. (13) University Hospital of Besançon, Besançon, France. (14) EFS-BFC, Besançon, France. (15) Université de Franche-Comté, EFS, INSERM, UMR RIGHT, F-25000 Besançon, France, Besançon, Bourgogne-Franche-Comté, France. (16) Ludwig Institute for Cancer Research and Department of Oncology, University of Lausanne, Lausanne, Switzerland. (17) University Hospital of Lausanne, Lausanne, Switzerland. (18) University of Geneva, Geneva, Switzerland. (19) Université de Franche-Comté, CHU Besançon, EFS, INSERM, UMR RIGHT, F-25000 Besan̤on, France, Besançon, France. (20) INSERM CIC-1431, Clinical Investigation Center in Biotherapy, University Hospital of Besançon, F-25000 Besançon, France, France. (21) INSERM, UMR1098, Besançon cedex, France. (22) University of Franche-Comté, Besançon, France. (23) University Hospital of Besançon, France. (24) university hospital of Besançon, Besançon, France. (25)Université de Franche-Comté, EFS, INSERM, UMR RIGHT, F-25000 Besançon, France, Besançon, France.

Author Info: (1) Department of Clinical Biochemistry, Faculty of Pharmacy and Laboratory Medicine, Army Medical University, Chongqing 400038, China. (2) Department of Clinical Biochemistry, Fac

Author Info: (1) Department of Clinical Biochemistry, Faculty of Pharmacy and Laboratory Medicine, Army Medical University, Chongqing 400038, China. (2) Department of Clinical Biochemistry, Faculty of Pharmacy and Laboratory Medicine, Army Medical University, Chongqing 400038, China. (3) Department of Clinical Biochemistry, Faculty of Pharmacy and Laboratory Medicine, Army Medical University, Chongqing 400038, China. (4) Department of Clinical Biochemistry, Faculty of Pharmacy and Laboratory Medicine, Army Medical University, Chongqing 400038, China. (5) Department of Clinical Biochemistry, Faculty of Pharmacy and Laboratory Medicine, Army Medical University, Chongqing 400038, China. (6) Department of Clinical Biochemistry, Faculty of Pharmacy and Laboratory Medicine, Army Medical University, Chongqing 400038, China. (7) Department of Clinical Biochemistry, Faculty of Pharmacy and Laboratory Medicine, Army Medical University, Chongqing 400038, China. (8) College of Education and Science, Chongqing Normal University, Chongqing 400047, China. (9) Department of Clinical Biochemistry, Faculty of Pharmacy and Laboratory Medicine, Army Medical University, Chongqing 400038, China. (10) Department of Clinical Biochemistry, Faculty of Pharmacy and Laboratory Medicine, Army Medical University, Chongqing 400038, China. (11) Department of Clinical Biochemistry, Faculty of Pharmacy and Laboratory Medicine, Army Medical University, Chongqing 400038, China. (12) Department of Clinical Biochemistry, Faculty of Pharmacy and Laboratory Medicine, Army Medical University, Chongqing 400038, China. Electronic address: yangmingzhen0807@126.com. (13) National Engineering Research Center of Immunological Products, Department of Microbiology and Biochemical Pharmacy, Faculty of Pharmacy and Laboratory Medicine, Army Medical University, Chongqing 400038, China. Electronic address: qmzou2007@163.com. (14) Department of Clinical Biochemistry, Faculty of Pharmacy and Laboratory Medicine, Army Medical University, Chongqing 400038, China. Electronic address: lianjiqin@tmmu.edu.cn.

Author Info: (1) Harvey Cushing Neuro-Oncology Laboratories, Department of Neurosurgery and Center for Tumors of the Nervous System, Mass General Brigham Cancer Institute and Harvard Medical Sc

Author Info: (1) Harvey Cushing Neuro-Oncology Laboratories, Department of Neurosurgery and Center for Tumors of the Nervous System, Mass General Brigham Cancer Institute and Harvard Medical School, Boston, MA 02115, USA. (2) Surgical Brain Mapping and Molecular Imaging Laboratory, Department of Neurosurgery, Mass General Brigham Cancer Institute and Harvard Medical School, Boston, MA 02115, USA. (3) Department of Pathology, Mass General Brigham Cancer Institute and Harvard Medical School, Boston, MA 02115, USA. Department of Pathology, Dana-Farber Cancer Institute and Harvard Medical School, Boston, MA 02115, USA. (4) James P. Allison Institute, University of Texas MD Anderson Cancer Hospital, Houston, TX 77030, USA. (5) Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA. (6) Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA. (7) Harvey Cushing Neuro-Oncology Laboratories, Department of Neurosurgery and Center for Tumors of the Nervous System, Mass General Brigham Cancer Institute and Harvard Medical School, Boston, MA 02115, USA. (8) Harvey Cushing Neuro-Oncology Laboratories, Department of Neurosurgery and Center for Tumors of the Nervous System, Mass General Brigham Cancer Institute and Harvard Medical School, Boston, MA 02115, USA. (9) Harvey Cushing Neuro-Oncology Laboratories, Department of Neurosurgery and Center for Tumors of the Nervous System, Mass General Brigham Cancer Institute and Harvard Medical School, Boston, MA 02115, USA. (10) Harvey Cushing Neuro-Oncology Laboratories, Department of Neurosurgery and Center for Tumors of the Nervous System, Mass General Brigham Cancer Institute and Harvard Medical School, Boston, MA 02115, USA. (11) Surgical Brain Mapping and Molecular Imaging Laboratory, Department of Neurosurgery, Mass General Brigham Cancer Institute and Harvard Medical School, Boston, MA 02115, USA. (12) Surgical Brain Mapping and Molecular Imaging Laboratory, Department of Neurosurgery, Mass General Brigham Cancer Institute and Harvard Medical School, Boston, MA 02115, USA. (13) Department of Pathology, Mass General Brigham Cancer Institute and Harvard Medical School, Boston, MA 02115, USA. Department of Pathology, Dana-Farber Cancer Institute and Harvard Medical School, Boston, MA 02115, USA. (14) Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA. (15) Department of Neurosurgery, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA. (16) Harvey Cushing Neuro-Oncology Laboratories, Department of Neurosurgery and Center for Tumors of the Nervous System, Mass General Brigham Cancer Institute and Harvard Medical School, Boston, MA 02115, USA. Department of Pathology, Mass General Brigham Cancer Institute and Harvard Medical School, Boston, MA 02115, USA. (17) Surgical Brain Mapping and Molecular Imaging Laboratory, Department of Neurosurgery, Mass General Brigham Cancer Institute and Harvard Medical School, Boston, MA 02115, USA. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA. Broad Institute, Massachusetts Institute of Technology, Cambridge, MA 02139, USA. Department of Neurology and Neurosurgery, McGill University, Montreal, QC H3AOG4, Canada. (18) Department of Pathology, Mass General Brigham Cancer Institute and Harvard Medical School, Boston, MA 02115, USA. Department of Pathology, Dana-Farber Cancer Institute and Harvard Medical School, Boston, MA 02115, USA. (19) Department of Pathology, Mass General Brigham Cancer Institute and Harvard Medical School, Boston, MA 02115, USA. Department of Pathology, Dana-Farber Cancer Institute and Harvard Medical School, Boston, MA 02115, USA. (20) Department of Neurosurgery, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA. (21) James P. Allison Institute, University of Texas MD Anderson Cancer Hospital, Houston, TX 77030, USA. (22) James P. Allison Institute, University of Texas MD Anderson Cancer Hospital, Houston, TX 77030, USA. (23) Department of Radiation Oncology, University of Texas MD Anderson Cancer Hospital, Houston, TX 77030, USA. (24) Department of Pathology, Johns Hopkins University Medical Center, Baltimore, MD 21205, USA. (25) Department of Medical Oncology, Dana-Farber Cancer Institute and Harvard Medical School, Boston, MA 02115, USA. (26) Department of Neurosurgery, University of Texas MD Anderson Cancer Hospital, Houston, TX 77030, USA. (27) Department of Neuro-Oncology, University of Texas MD Anderson Cancer Hospital, Houston, TX 77030, USA. (28) Department of Neurosurgery, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA. (29) Department of Neurosurgery, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA. (30) Department of Neurology, Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA. (31) Division of Neuro-Oncology, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University Medical Center, Baltimore, MD 21205, USA. (32) Department of Neurosurgery, Johns Hopkins University Medical Center, Baltimore, MD 21205, USA. (33) Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA. (34) Department of Pathology, Mass General Brigham Cancer Institute and Harvard Medical School, Boston, MA 02115, USA. Department of Pathology, Dana-Farber Cancer Institute and Harvard Medical School, Boston, MA 02115, USA. (35) Department of Biostatistics, University of Texas MD Anderson Cancer Hospital, Houston, TX 77030, USA. (36) Candel Therapeutics Inc., Needham, MA 02494, USA. Accelerating GBM Therapies TeamLab, Cambridge, MA 02142, USA. (37) James P. Allison Institute, University of Texas MD Anderson Cancer Hospital, Houston, TX 77030, USA. Department of Immunology, University of Texas MD Anderson Cancer Hospital, Houston, TX 77030, USA. (38) Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA. (39) Department of Pathology, Mass General Brigham Cancer Institute and Harvard Medical School, Boston, MA 02115, USA. Department of Pathology, Dana-Farber Cancer Institute and Harvard Medical School, Boston, MA 02115, USA. (40) Surgical Brain Mapping and Molecular Imaging Laboratory, Department of Neurosurgery, Mass General Brigham Cancer Institute and Harvard Medical School, Boston, MA 02115, USA. (41) Center for Neuro-Oncology, Dana-Farber Cancer Institute and Harvard Medical School, Boston, MA 02115, USA. (42) Broad Institute, Massachusetts Institute of Technology, Cambridge, MA 02139, USA. Department of Medical Oncology, Dana-Farber Cancer Institute and Harvard Medical School, Boston, MA 02115, USA. (43) Harvey Cushing Neuro-Oncology Laboratories, Department of Neurosurgery and Center for Tumors of the Nervous System, Mass General Brigham Cancer Institute and Harvard Medical School, Boston, MA 02115, USA.