CSF1R+ myeloid-monocytic cells drive CAR-T cell resistance in aggressive B cell lymphoma
CAR T cell therapies are well known for their potent capacity for killing antigen-expressing target cells. However, they are often hindered by factors in solid tumors and by challenges related to the development of an autologous T cell product...
Recent discoveries of unmutated aberrantly expressed tumor-specific antigens (aeTSAs) derived from non-coding regions and embryonic transcriptional programs has garnered attention as targets for immunotherapy. Apavaloaei et al. explored cell surface presentation of peptide:MHCs derived from mutated and unmutated tumor...
The ACIR team attended the 22nd CIMT Annual Meeting 2025 in Mainz, Germany. This week’s extensive special feature covers select talks from the conference. We have organized the content by topics below. CIMT Lifetime achievement awardRolf Kiessling Keynote addressCornelis...
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