Author Info: (1) Department of Microbiology and Immunology, Stanford University School of Medicine, Stanford, CA, USA. (2) Department of Integrative Physiology, University of Colorado Boulder,

Author Info: (1) Department of Microbiology and Immunology, Stanford University School of Medicine, Stanford, CA, USA. (2) Department of Integrative Physiology, University of Colorado Boulder, Boulder, CO, USA. (3) Department of Pathology, Stanford University, Stanford, CA, USA. Stanford Cancer Institute, Stanford University, Palo Alto, CA, USA. (4) Department of Microbiology and Immunology, Stanford University School of Medicine, Stanford, CA, USA. jsonnenburg@stanford.edu. Chan Zuckerberg Biohub, San Francisco, CA, USA. jsonnenburg@stanford.edu. Center for Human Microbiome Studies, Stanford University School of Medicine, Stanford, CA, USA. jsonnenburg@stanford.edu.

Author Info: (1) Division of Experimental Neurosurgery, Department of Neurosurgery, Heidelberg University Hospital, Medical Faculty Heidelberg, Heidelberg University, Heidelberg, Germany; Divis

Author Info: (1) Division of Experimental Neurosurgery, Department of Neurosurgery, Heidelberg University Hospital, Medical Faculty Heidelberg, Heidelberg University, Heidelberg, Germany; Division of Molecular Genetics, German Cancer Research Center (DKFZ), Heidelberg, Germany. Electronic address: lena.jassowicz@med.uni-heidelberg.de. (2) Division of Molecular Genetics, German Cancer Research Center (DKFZ), Heidelberg, Germany. (3) Division of Experimental Neurosurgery, Department of Neurosurgery, Heidelberg University Hospital, Medical Faculty Heidelberg, Heidelberg University, Heidelberg, Germany. (4) Department of Biostatistics, Oslo Centre for Biostatistics and Epidemiology, Institute of Basic Medical Sciences, University of Oslo, Oslo, Norway. (5) Division of Experimental Neurosurgery, Department of Neurosurgery, Heidelberg University Hospital, Medical Faculty Heidelberg, Heidelberg University, Heidelberg, Germany. (6) Division of Molecular Genetics, German Cancer Research Center (DKFZ), Heidelberg, Germany; Faculty of Biosciences, Heidelberg University, Heidelberg, Germany. (7) Division of Experimental Neurosurgery, Department of Neurosurgery, Heidelberg University Hospital, Medical Faculty Heidelberg, Heidelberg University, Heidelberg, Germany. (8) Division of Experimental Neurosurgery, Department of Neurosurgery, Heidelberg University Hospital, Medical Faculty Heidelberg, Heidelberg University, Heidelberg, Germany. (9) Division of Experimental Neurosurgery, Department of Neurosurgery, Heidelberg University Hospital, Medical Faculty Heidelberg, Heidelberg University, Heidelberg, Germany. (10) Division of Molecular Genetics, German Cancer Research Center (DKFZ), Heidelberg, Germany. (11) Division of Experimental Neurosurgery, Department of Neurosurgery, Heidelberg University Hospital, Medical Faculty Heidelberg, Heidelberg University, Heidelberg, Germany; Division of Molecular Genetics, German Cancer Research Center (DKFZ), Heidelberg, Germany. (12) Division of Molecular Genetics, German Cancer Research Center (DKFZ), Heidelberg, Germany. (13) Division of Experimental Neurosurgery, Department of Neurosurgery, Heidelberg University Hospital, Medical Faculty Heidelberg, Heidelberg University, Heidelberg, Germany; Department of Neurosurgery, Heidelberg University Hospital, Medical Faculty Heidelberg, Heidelberg University, Heidelberg, Germany. (14) Division Immune Regulation in Cancer, German Cancer Research Center (DKFZ), Heidelberg, Germany. (15) Division of Molecular and Translational Radiation Oncology and Clinical Cooperation Unit Translational Radiation Oncology, German Cancer Research Center (DKFZ) and Heidelberg University Hospital, Heidelberg, Germany. (16) Division of Molecular and Translational Radiation Oncology and Clinical Cooperation Unit Translational Radiation Oncology, German Cancer Research Center (DKFZ) and Heidelberg University Hospital, Heidelberg, Germany. (17) Division of Chromatin Networks, German Cancer Research Center (DKFZ) and Bioquant, Heidelberg, Germany. (18) Division of Experimental Neurosurgery, Department of Neurosurgery, Heidelberg University Hospital, Medical Faculty Heidelberg, Heidelberg University, Heidelberg, Germany; Department of Neurosurgery, Heidelberg University Hospital, Medical Faculty Heidelberg, Heidelberg University, Heidelberg, Germany. (19) Division of Experimental Neurosurgery, Department of Neurosurgery, Heidelberg University Hospital, Medical Faculty Heidelberg, Heidelberg University, Heidelberg, Germany; Department of Neurosurgery, Heidelberg University Hospital, Medical Faculty Heidelberg, Heidelberg University, Heidelberg, Germany. (20) Division of Experimental Neurosurgery, Department of Neurosurgery, Heidelberg University Hospital, Medical Faculty Heidelberg, Heidelberg University, Heidelberg, Germany; Department of Neurosurgery, Heidelberg University Hospital, Medical Faculty Heidelberg, Heidelberg University, Heidelberg, Germany. (21) Division of Pediatric Neurooncology, German Cancer Research Center (DKFZ), and Hopp Children's Cancer Center at the NCT Heidelberg (KiTZ), Heidelberg, Germany. (22) Hamamatsu Tissue Imaging and Analysis Center, BioQuant, University of Heidelberg, Heidelberg, Germany. (23) Division of Experimental Neurosurgery, Department of Neurosurgery, Heidelberg University Hospital, Medical Faculty Heidelberg, Heidelberg University, Heidelberg, Germany. (24) Division of Experimental Neurosurgery, Department of Neurosurgery, Heidelberg University Hospital, Medical Faculty Heidelberg, Heidelberg University, Heidelberg, Germany. (25) Division of Experimental Neurosurgery, Department of Neurosurgery, Heidelberg University Hospital, Medical Faculty Heidelberg, Heidelberg University, Heidelberg, Germany. (26) Department of Biostatistics, Oslo Centre for Biostatistics and Epidemiology, Institute of Basic Medical Sciences, University of Oslo, Oslo, Norway; Oslo Centre for Biostatistics and Epidemiology, Research Support Services, Oslo University Hospital, Oslo, Norway. (27) Single Cell Open Lab, German Cancer Research Center (DKFZ), Heidelberg, Germany. (28) Single Cell Open Lab, German Cancer Research Center (DKFZ), Heidelberg, Germany. (29) National Center for Tumor Diseases (NCT), NCT Heidelberg, a Partnership Between the German Cancer Research Center (DKFZ), the University Hospital Heidelberg (UKHD), The Heidelberg Medical Faculty of the Heidelberg University, and the Thorax Clinic Heidelberg, Heidelberg, Germany. (30) Department of Medical Oncology, Heidelberg University Hospital, Medical Faculty Heidelberg, Heidelberg University, Heidelberg, Germany. (31) National Center for Tumor Diseases (NCT), NCT Heidelberg, a Partnership Between the German Cancer Research Center (DKFZ), the University Hospital Heidelberg (UKHD), The Heidelberg Medical Faculty of the Heidelberg University, and the Thorax Clinic Heidelberg, Heidelberg, Germany. (32) National Center for Tumor Diseases (NCT), NCT Heidelberg, a Partnership Between the German Cancer Research Center (DKFZ), the University Hospital Heidelberg (UKHD), The Heidelberg Medical Faculty of the Heidelberg University, and the Thorax Clinic Heidelberg, Heidelberg, Germany; Department of Medical Oncology, Heidelberg University Hospital, Medical Faculty Heidelberg, Heidelberg University, Heidelberg, Germany; Department of Gynecology and Obstetrics, Heidelberg University Hospital, Medical Faculty Heidelberg, Heidelberg University, Heidelberg, Germany. (33) Division Immune Regulation in Cancer, German Cancer Research Center (DKFZ), Heidelberg, Germany. (34) Division of Chromatin Networks, German Cancer Research Center (DKFZ) and Bioquant, Heidelberg, Germany. (35) Division of Molecular and Translational Radiation Oncology and Clinical Cooperation Unit Translational Radiation Oncology, German Cancer Research Center (DKFZ) and Heidelberg University Hospital, Heidelberg, Germany. (36) Department of Neuropathology, Institute of Pathology, Heidelberg University Hospital, Medical Faculty Heidelberg, Heidelberg University, Heidelberg, Germany. (37) Department of Neurosurgery, Heidelberg University Hospital, Medical Faculty Heidelberg, Heidelberg University, Heidelberg, Germany. (38) Department of Neurosurgery, Heidelberg University Hospital, Medical Faculty Heidelberg, Heidelberg University, Heidelberg, Germany. (39) Single Cell Open Lab, German Cancer Research Center (DKFZ), Heidelberg, Germany. (40) Division of Molecular Genetics, German Cancer Research Center (DKFZ), Heidelberg, Germany; National Center for Tumor Diseases (NCT), NCT Heidelberg, a Partnership Between the German Cancer Research Center (DKFZ), the University Hospital Heidelberg (UKHD), The Heidelberg Medical Faculty of the Heidelberg University, and the Thorax Clinic Heidelberg, Heidelberg, Germany. (41) Division of Molecular Genetics, German Cancer Research Center (DKFZ), Heidelberg, Germany. (42) Division of Molecular Genetics, German Cancer Research Center (DKFZ), Heidelberg, Germany. Electronic address: m.seiffert@dkfz-heidelberg.de. (43) Division of Experimental Neurosurgery, Department of Neurosurgery, Heidelberg University Hospital, Medical Faculty Heidelberg, Heidelberg University, Heidelberg, Germany. Electronic address: h.mende@med.uni-heidelberg.de.

Author Info: (1) Department of Biomedicine, University Hospital and University of Basel, Basel, Switzerland. (2) Aix Marseille UniversitŽ, CNRS, INSERM, Centre d'Immunologie de Marseille-Luminy

Author Info: (1) Department of Biomedicine, University Hospital and University of Basel, Basel, Switzerland. (2) Aix Marseille UniversitŽ, CNRS, INSERM, Centre d'Immunologie de Marseille-Luminy, Marseille, France. (3) Department of Biomedicine, University Hospital and University of Basel, Basel, Switzerland. (4) Institute of Transplant Immunology, Hannover Medical School, Hannover, Germany. (5) Department of Biomedicine, University Hospital and University of Basel, Basel, Switzerland. (6) Department of Biomedicine, University Hospital and University of Basel, Basel, Switzerland. (7) Institute of Transplant Immunology, Hannover Medical School, Hannover, Germany. (8) Institute of Transplant Immunology, Hannover Medical School, Hannover, Germany. (9) Institute of Transplant Immunology, Hannover Medical School, Hannover, Germany. (10) Department of Biomedicine, University Hospital and University of Basel, Basel, Switzerland. (11) Department of Biomedicine, University Hospital and University of Basel, Basel, Switzerland. (12) Institute of Pathology, University Hospital and University of Basel, Basel, Switzerland. (13) Department of Biomedicine, University Hospital and University of Basel, Basel, Switzerland. (14) Department of Biomedicine, University Hospital and University of Basel, Basel, Switzerland. (15) Department of Biomedicine, University Hospital and University of Basel, Basel, Switzerland. Roche Pharma Research and Early Development pRED, Roche Innovation Center, Basel, Switzerland. (16) Department of Biomedicine, University Hospital and University of Basel, Basel, Switzerland. (17) Department of Thoracic Surgery, University Hospital Basel, Basel, Switzerland. (18) Department of Thoracic Surgery, University Hospital Basel, Basel, Switzerland. (19) German Centre for Lung Diseases (DZL), BREATH site, Hannover, Germany. Institute of Pathology, Hannover Medical School, Hannover, Germany. (20) Department of Biomedicine, University Hospital and University of Basel, Basel, Switzerland. Medical Oncology, University Hospital Basel, Basel, Switzerland. (21) Institute of Pathology, University Hospital and University of Basel, Basel, Switzerland. (22) Department of Biomedicine, University Hospital and University of Basel, Basel, Switzerland. (23) Department of Biomedicine, University Hospital and University of Basel, Basel, Switzerland. (24) Department of Biomedicine, University Hospital and University of Basel, Basel, Switzerland. (25) Institute of Pathology, University Hospital and University of Basel, Basel, Switzerland. (26) Department of Biomedicine, University Hospital and University of Basel, Basel, Switzerland. Medical Oncology, University Hospital Basel, Basel, Switzerland. (27) Institute of Transplant Immunology, Hannover Medical School, Hannover, Germany. German Centre for Lung Diseases (DZL), BREATH site, Hannover, Germany. German Centre for Infection Research (DZIF), TTU-IICH, Hannover/Braunschweig site, Hannover, Germany. (28) Department of Biomedicine, University Hospital and University of Basel, Basel, Switzerland. (29) Aix Marseille UniversitŽ, CNRS, INSERM, Centre d'Immunologie de Marseille-Luminy, Marseille, France. APHM, H™pital de la Timone, Marseille-Immunop™le Profiling Platform, Marseille, France. Paris-Saclay Cancer Cluster, Villejuif, France. Ecole Polytechnique, Palaiseau, France. (30) Roche Pharma Research and Early Development pRED, Roche Innovation Center, Basel, Switzerland. (31) Department of Biomedicine, University Hospital and University of Basel, Basel, Switzerland. Medical Oncology, University Hospital Basel, Basel, Switzerland.

Author Info: (1) Lab of Dendritic Cell Biology and Cancer Immunotherapy, VIB Center for Inflammation Research, Brussels, Belgium. Lab of Cellular and Molecular Immunology, Brussels Center for I

Author Info: (1) Lab of Dendritic Cell Biology and Cancer Immunotherapy, VIB Center for Inflammation Research, Brussels, Belgium. Lab of Cellular and Molecular Immunology, Brussels Center for Immunology, Vrije Universiteit Brussel, Brussels, Belgium. Lab of Tumor Immunology and Immunotherapy, Department of Oncology, Leuven Cancer Institute, KU Leuven, Leuven, Belgium. (2) Lab of Dendritic Cell Biology and Cancer Immunotherapy, VIB Center for Inflammation Research, Brussels, Belgium. Lab of Cellular and Molecular Immunology, Brussels Center for Immunology, Vrije Universiteit Brussel, Brussels, Belgium. (3) Lab of Dendritic Cell Biology and Cancer Immunotherapy, VIB Center for Inflammation Research, Brussels, Belgium. Lab of Cellular and Molecular Immunology, Brussels Center for Immunology, Vrije Universiteit Brussel, Brussels, Belgium. (4) Laboratory for Translational Genetics, Department of Human Genetics, KU Leuven, Leuven, Belgium. Laboratory for Translational Genetics, VIB Center for Cancer Biology, Leuven, Belgium. (5) Laboratory for ER Stress and Inflammation, VIB Center for Inflammation Research, Ghent, Belgium. Department of Internal Medicine and Pediatrics, Ghent University, Ghent, Belgium. Laboratory for Barriers in Inflammation, VIB Center for Inflammation Research, Ghent, Belgium. Department of Biomedical Molecular Biology, Ghent University, Ghent, Belgium. (6) Lab of Dendritic Cell Biology and Cancer Immunotherapy, VIB Center for Inflammation Research, Brussels, Belgium. Lab of Cellular and Molecular Immunology, Brussels Center for Immunology, Vrije Universiteit Brussel, Brussels, Belgium. (7) Department of Biomedical Molecular Biology, Ghent University, Ghent, Belgium. VIB Single Cell Core; VIB, Ghent-Leuven, Belgium. (8) Swiss Institute for Experimental Cancer Research (ISREC), School of Life Sciences, Swiss Federal Institute of Technology in Lausanne (EPFL), Lausanne, Switzerland. Agora Cancer Research Center, Lausanne, Switzerland. (9) Laboratory of Cancer Signaling, GIGA-Institute, University of Lige, Lige, Belgium. (10) Laboratory of Cancer Signaling, GIGA-Institute, University of Lige, Lige, Belgium. (11) Lab of Cellular and Molecular Immunology, Brussels Center for Immunology, Vrije Universiteit Brussel, Brussels, Belgium. (12) Department of Biomedical Molecular Biology, Ghent University, Ghent, Belgium. VIB Single Cell Core; VIB, Ghent-Leuven, Belgium. (13) Lab of Dendritic Cell Biology and Cancer Immunotherapy, VIB Center for Inflammation Research, Brussels, Belgium. Lab of Cellular and Molecular Immunology, Brussels Center for Immunology, Vrije Universiteit Brussel, Brussels, Belgium. (14) Laboratory of Cancer Signaling, GIGA-Institute, University of Lige, Lige, Belgium. Laboratory of Metabolic Regulation, GIGA-Institute, University of Lige, Lige, Belgium. (15) Laboratory of Cancer Signaling, GIGA-Institute, University of Lige, Lige, Belgium. WELBIO Department, WEL Research Institute, Wavre, Belgium. (16) Laboratory for ER Stress and Inflammation, VIB Center for Inflammation Research, Ghent, Belgium. Department of Internal Medicine and Pediatrics, Ghent University, Ghent, Belgium. (17) Swiss Institute for Experimental Cancer Research (ISREC), School of Life Sciences, Swiss Federal Institute of Technology in Lausanne (EPFL), Lausanne, Switzerland. Agora Cancer Research Center, Lausanne, Switzerland. (18) Laboratory for Translational Genetics, Department of Human Genetics, KU Leuven, Leuven, Belgium. Laboratory for Translational Genetics, VIB Center for Cancer Biology, Leuven, Belgium. (19) Lab of Tumor Immunology and Immunotherapy, Department of Oncology, Leuven Cancer Institute, KU Leuven, Leuven, Belgium. (20) Lab of Dendritic Cell Biology and Cancer Immunotherapy, VIB Center for Inflammation Research, Brussels, Belgium. dlaoui@vub.be. Lab of Cellular and Molecular Immunology, Brussels Center for Immunology, Vrije Universiteit Brussel, Brussels, Belgium. dlaoui@vub.be.

Author Info: (1) Roche Pharma Research and Early Development, Roche Innovation Center Zurich, Schlieren, Switzerland. (2) Roche Pharma Research and Early Development, Roche Innovation Center Ba

Author Info: (1) Roche Pharma Research and Early Development, Roche Innovation Center Zurich, Schlieren, Switzerland. (2) Roche Pharma Research and Early Development, Roche Innovation Center Basel, Basel, Switzerland. (3) Roche Pharma Research and Early Development, Roche Innovation Center Zurich, Schlieren, Switzerland. (4) Roche Pharma Research and Early Development, Roche Innovation Center Zurich, Schlieren, Switzerland. (5) Roche Pharma Research and Early Development, Roche Innovation Center Zurich, Schlieren, Switzerland. (6) Roche Pharma Research and Early Development, Roche Innovation Center Basel, Basel, Switzerland. (7) Roche Pharma Research and Early Development, Roche Innovation Center Zurich, Schlieren, Switzerland. (8) Roche Pharma Research and Early Development, Roche Innovation Center Basel, Basel, Switzerland. (9) Roche Pharma Research and Early Development, Roche Innovation Center Zurich, Schlieren, Switzerland. (10) Roche Pharma Research and Early Development, Roche Innovation Center Zurich, Schlieren, Switzerland. (11) Institute of Experimental Immunology, UniversitŠt ZŸrich, ZŸrich, Switzerland. Department of Immunology, Heidelberg University Medical Faculty Mannheim, Mannheim, Germany. (12) Roche Pharma Research and Early Development, Roche Innovation Center Zurich, Schlieren, Switzerland. (13) Roche Pharma Research and Early Development, Roche Innovation Center Basel, Basel, Switzerland leo.kunz@roche.com.

Author Info: (1) Oslo Center for Biostatistics and Epidemiology, University of Oslo, Oslo, Norway. younessazimzade@gmail.com. (2) Department of Tumor Biology, Institute for Cancer Research, Div

Author Info: (1) Oslo Center for Biostatistics and Epidemiology, University of Oslo, Oslo, Norway. younessazimzade@gmail.com. (2) Department of Tumor Biology, Institute for Cancer Research, Division of Cancer Medicine, Oslo University Hospital, The Norwegian Radium Hospital, Oslo, Norway. (3) Department of Medical Genetics, Oslo University Hospital, University of Oslo, Oslo, Norway. (4) Oslo Center for Biostatistics and Epidemiology, University of Oslo, Oslo, Norway. arnoldo.frigessi@medisin.uio.no. Oslo Center for Biostatistics and Epidemiology, Oslo University Hospital, Oslo, Norway. arnoldo.frigessi@medisin.uio.no. (5) Oslo Center for Biostatistics and Epidemiology, University of Oslo, Oslo, Norway. a.k.luque@medisin.uio.no. Oslo Center for Biostatistics and Epidemiology, Oslo University Hospital, Oslo, Norway. a.k.luque@medisin.uio.no.

Author Info: (1) University of Michigan-Ann Arbor Ann Arbor, MI United States. ROR: https://ror.org/00jmfr291 (2) University of Michigan-Ann Arbor Ann Arbor, MI United States. (3) University of

Author Info: (1) University of Michigan-Ann Arbor Ann Arbor, MI United States. ROR: https://ror.org/00jmfr291 (2) University of Michigan-Ann Arbor Ann Arbor, MI United States. (3) University of Michigan-Ann Arbor Ann Arbor, Michigan United States. ROR: https://ror.org/00jmfr291 (4) University of Michigan Medical Schooligan United States. (5) University of Michigan-Ann Arbor Ann Arbor, Michigan United States. ROR: https://ror.org/00jmfr291 (6) University of Michigan-Ann Arbor Ann Arbor, Michigan United States. ROR: https://ror.org/00jmfr291 (7) University of Michigan-Ann Arbor Ann Arbor, MI United States. ROR: https://ror.org/00jmfr291 (8) University of Michigan-Ann Arbor Ann Arbor, MI United States. ROR: https://ror.org/00jmfr291 (9) University of Michigan-Ann Arbor Ann Arbor, MI United States. ROR: https://ror.org/00jmfr291 (10) University of Michigan-Ann Arbor Ann Arbor, MI United States. ROR: https://ror.org/00jmfr291 (11) University of Michigan-Ann Arbor Ann Arbor United States. ROR: https://ror.org/00jmfr291 (12) University of Michigan-Ann Arbor United States. ROR: https://ror.org/00jmfr291 (13) University of Maryland, Baltimore Baltimore United States. ROR: https://ror.org/04rq5mt64 (14) University of Michigan-Ann Arbor Ann Arbor, Michigan United States. ROR: https://ror.org/00jmfr291 (15) University of Michigan-Ann Arbor Ann Arbor United States. ROR: https://ror.org/00jmfr291 (16) University of Michigan-Ann Arbor United States. ROR: https://ror.org/00jmfr291 (17) University of Michigan-Ann Arbor United States. ROR: https://ror.org/00jmfr291 (18) University of Michigan-Ann Arbor Ann Arbor, Michigan United States. ROR: https://ror.org/00jmfr291 (19) University of Michigan-Ann Arbor United States. ROR: https://ror.org/00jmfr291 (20) University of Michigan-Ann Arbor Ann Arbor, Michigan United States. ROR: https://ror.org/00jmfr291 (21) University of Michigan-Ann Arbor Ann Arbor, Michigan United States. ROR: https://ror.org/00jmfr291 (22) University of Michigan-Ann Arbor Ann Arbor, Michigan United States. ROR: https://ror.org/00jmfr291 (23) University of Michigan-Ann Arbor Ann Arbor United States. ROR: https://ror.org/00jmfr291 (24) University of Michigan-Ann Arbor United States. ROR: https://ror.org/00jmfr291 (25) Cornell University Ithaca United States. ROR: https://ror.org/05bnh6r87 (26) University of Michigan-Ann Arbor Ann Arbor, MI United States. ROR: https://ror.org/00jmfr291 (27) University of Michigan-Ann Arbor Ann Arbor, MI United States. ROR: https://ror.org/00jmfr291 (28) University of Michigan-Ann Arbor Ann Arbor, Michigan United States. ROR: https://ror.org/00jmfr291 (29) University of Michigan-Ann Arbor Ann Arbor, MI United States. ROR: https://ror.org/00jmfr291 (30) University of Michigan-Ann Arbor Ann Arbor, MI United States. ROR: https://ror.org/00jmfr291 (31) Cedars-Sinai Medical Center Los Angeles, CA United States. ROR: https://ror.org/02pammg90 (32) University of Michigan-Ann Arbor Ann Arbor, MI United States. ROR: https://ror.org/00jmfr291 (33) University of Michigan-Ann Arbor Ann Arbor, MI United States. ROR: https://ror.org/00jmfr291

Author Info: (1) State Key Laboratory of Systems Medicine for Cancer, Shanghai Cancer Institute & Department of Liver Surgery, Renji Hospital, Shanghai Jiao Tong University School of Medicine,

Author Info: (1) State Key Laboratory of Systems Medicine for Cancer, Shanghai Cancer Institute & Department of Liver Surgery, Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. (2) State Key Laboratory of Systems Medicine for Cancer, Shanghai Cancer Institute & Department of Liver Surgery, Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. (3) State Key Laboratory of Systems Medicine for Cancer, Shanghai Cancer Institute & Department of Liver Surgery, Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China; Shanghai Immune Therapy Institute, Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. (4) Institute of Molecular Medicine, Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. (5) State Key Laboratory of Systems Medicine for Cancer, Shanghai Cancer Institute & Department of Liver Surgery, Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. (6) State Key Laboratory of Systems Medicine for Cancer, Shanghai Cancer Institute & Department of Liver Surgery, Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. (7) State Key Laboratory of Systems Medicine for Cancer, Shanghai Cancer Institute & Department of Liver Surgery, Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. (8) Department of Liver Surgery and Transplantation, Key Laboratory of Carcinogenesis and Cancer Invasion, Liver Cancer Institute, Zhongshan Hospital, Fudan University, Shanghai, China. (9) State Key Laboratory of Systems Medicine for Cancer, Shanghai Cancer Institute & Department of Liver Surgery, Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. (10) Shanghai Institute of Immunology, Shanghai Jiao Tong University School of Medicine, Shanghai, China. (11) State Key Laboratory of Systems Medicine for Cancer, Shanghai Cancer Institute & Department of Liver Surgery, Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. (12) State Key Laboratory of Systems Medicine for Cancer, Shanghai Cancer Institute & Department of Liver Surgery, Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. (13) State Key Laboratory of Systems Medicine for Cancer, Shanghai Cancer Institute & Department of Liver Surgery, Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. (14) The Third Department of Hepatic Surgery, Eastern Hepatobiliary Surgery Hospital, Shanghai, China. (15) Department of Liver Surgery and Transplantation, Key Laboratory of Carcinogenesis and Cancer Invasion, Liver Cancer Institute, Zhongshan Hospital, Fudan University, Shanghai, China. (16) German Cancer Research Center, Division Immune Regulation in Cancer, Heidelberg, Germany. (17) State Key Laboratory of Systems Medicine for Cancer, Shanghai Cancer Institute & Department of Liver Surgery, Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China; Division of Molecular Carcinogenesis, Oncode Institute, the Netherlands Cancer Institute, Amsterdam, the Netherlands. Electronic address: r.bernards@nki.nl. (18) Institute of Molecular Medicine, Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. Electronic address: yuyang@shsmu.edu.cn. (19) State Key Laboratory of Systems Medicine for Cancer, Shanghai Cancer Institute & Department of Liver Surgery, Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. Electronic address: wxqin@sjtu.edu.cn. (20) State Key Laboratory of Systems Medicine for Cancer, Shanghai Cancer Institute & Department of Liver Surgery, Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. Electronic address: cwang@shsci.org.

Author Info: (1) Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX, USA. (2) Department of Genomic Medicine, The University of Texas MD Anderson Can

Author Info: (1) Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX, USA. (2) Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX, USA. (3) Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX, USA. (4) Department of Genitourinary Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA. (5) Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX, USA. The University of Texas MD Anderson Cancer Center UTHealth Houston Graduate School of Biomedical Sciences; Houston, TX, USA. (6) Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX, USA. (7) Department of Translational Molecular Pathology, The University of Texas MD Anderson Cancer Center; Houston, TX, USA. (8) Centre de Recherche des Cordeliers, Sorbonne UniversitŽ, INSERM, Universite Paris Cite, Equipe labellisŽe Ligue Contre le Cancer, Paris, France. (9) Department of Translational Molecular Pathology, The University of Texas MD Anderson Cancer Center; Houston, TX, USA. (10) Department of Translational Molecular Pathology, The University of Texas MD Anderson Cancer Center; Houston, TX, USA. (11) Department of Translational Molecular Pathology, The University of Texas MD Anderson Cancer Center; Houston, TX, USA. (12) Laura and Isaac Perlmutter Cancer Center, Department of Medicine, New York University Grossman School of Medicine, NYU Langone Health, New York, NY, USA. (13) Department of Translational Molecular Pathology, The University of Texas MD Anderson Cancer Center; Houston, TX, USA. (14) Department of Translational Molecular Pathology, The University of Texas MD Anderson Cancer Center; Houston, TX, USA. (15) Department of Biostatistics, The University of North Carolina, Chapel Hill, NC, USA. Department of Genetics, The University of North Carolina, Chapel Hill, NC, USA. (16) Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX, USA. (17) Department of Translational Molecular Pathology, The University of Texas MD Anderson Cancer Center; Houston, TX, USA. (18) Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX, USA. (19) Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX, USA. (20) Therapeutics Discovery Division, The University of Texas MD Anderson Cancer Center, Houston, TX, USA. (21) Department of Translational Molecular Pathology, The University of Texas MD Anderson Cancer Center; Houston, TX, USA. (22) Department of Translational Molecular Pathology, The University of Texas MD Anderson Cancer Center; Houston, TX, USA. (23) Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX, USA. (24) Department of Gynecologic Oncology and Reproductive Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX, USA. (25) Department of Translational Molecular Pathology, The University of Texas MD Anderson Cancer Center; Houston, TX, USA. Department of Pathology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA. (26) Department of Biostatistics, Epidemiology and Informatics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA. (27) Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX, USA. (28) Department of Gynecologic Oncology and Reproductive Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX, USA. (29) Department of Translational Molecular Pathology, The University of Texas MD Anderson Cancer Center; Houston, TX, USA. (30) Department of Biostatistics, The University of Texas MD Anderson Cancer Center, Houston, TX, USA. (31) Department of Genitourinary Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA. The University of Texas MD Anderson Cancer Center UTHealth Houston Graduate School of Biomedical Sciences; Houston, TX, USA. (32) Department of Gastrointestinal Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA. (33) Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX, USA. (34) Department of Gynecologic Oncology and Reproductive Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX, USA. (35) Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX, USA. The University of Texas MD Anderson Cancer Center UTHealth Houston Graduate School of Biomedical Sciences; Houston, TX, USA. Department of Translational Molecular Pathology, The University of Texas MD Anderson Cancer Center; Houston, TX, USA. Department of Pathology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA. (36) Centre de Recherche des Cordeliers, Sorbonne UniversitŽ, INSERM, Universite Paris Cite, Equipe labellisŽe Ligue Contre le Cancer, Paris, France. (37) Centre de Recherche des Cordeliers, Sorbonne UniversitŽ, INSERM, Universite Paris Cite, Equipe labellisŽe Ligue Contre le Cancer, Paris, France. (38) Laura and Isaac Perlmutter Cancer Center, Department of Medicine, New York University Grossman School of Medicine, NYU Langone Health, New York, NY, USA. Department of Pathology, New York University Grossman School of Medicine, New York, NY, USA. (39) The University of Texas MD Anderson Cancer Center UTHealth Houston Graduate School of Biomedical Sciences; Houston, TX, USA. Department of Translational Molecular Pathology, The University of Texas MD Anderson Cancer Center; Houston, TX, USA. (40) Department of Genitourinary Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA. (41) Department of Genitourinary Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA. Department of Immunology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA. James P. Allison Institute, The University of Texas MD Anderson Cancer Center, Houston, TX, USA. (42) Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX, USA. The University of Texas MD Anderson Cancer Center UTHealth Houston Graduate School of Biomedical Sciences; Houston, TX, USA. James P. Allison Institute, The University of Texas MD Anderson Cancer Center, Houston, TX, USA. Institute for Data Science in Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA. Center for Cellular Language Intelligence, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.

Author Info: (1) China Pharmaceutical University Nanjing China. ROR: https://ror.org/01sfm2718 (2) China Pharmaceutical University Nanjing China. ROR: https://ror.org/01sfm2718 (3) China Pharma

Author Info: (1) China Pharmaceutical University Nanjing China. ROR: https://ror.org/01sfm2718 (2) China Pharmaceutical University Nanjing China. ROR: https://ror.org/01sfm2718 (3) China Pharmaceutical University Nanjing China. ROR: https://ror.org/01sfm2718 (4) China Pharmaceutical University Nanjing China. ROR: https://ror.org/01sfm2718 (5) China Pharmaceutical University China. ROR: https://ror.org/01sfm2718 (6) China Pharmaceutical University Nanjing China. ROR: https://ror.org/01sfm2718 (7) China Pharmaceutical University Nanjing China. ROR: https://ror.org/01sfm2718 (8) China Pharmaceutical University Nanjing China. ROR: https://ror.org/01sfm2718 (9) China Pharmaceutical University Nanjing China. ROR: https://ror.org/01sfm2718 (10) China Pharmaceutical University Nanjing China. ROR: https://ror.org/01sfm2718 (11) China Pharmaceutical University Nanjing China. ROR: https://ror.org/01sfm2718 (12) China Pharmaceutical University Nanjing China. ROR: https://ror.org/01sfm2718 (13) China Pharmaceutical University Nanjing China. ROR: https://ror.org/01sfm2718