This year, 2025, marks a special milestone: ACIR’s 10th anniversary! And we celebrate it with the announcement of a leadership transition. Dear Readers, The idea for ACIR was born in early 2015, just a few months after my son...
The spleen has gained interest as a vaccination target, as high uptake of therapeutic mRNA cancer vaccines by antigen-presenting cells (APCs) is needed for therapeutic efficacy. However, current formulations of mRNA vaccines contain lipid nanoparticles (LNPs) that accumulate in...
The antitumor efficacy of cancer immunotherapy often relies heavily on CD8+ and CD4+ T cell recognition of tumor antigens presented on MHC molecules. However, investigating settings with low or no tumor MHC expression, Kim and Haerr et al. found...
In November 2019, ACIR received the Visionary Award from the Cambridge Chamber of Commerce.
Watch the 3-minute video explaining ACIR's mission and goal:
In September 2020, ACIR was featured in the documentary The American Dream on Bloomberg TV.
Watch the 6-minute segment on the story behind your favorite digest here:
ACIR's mission is to fast-track cancer immunotherapy research by helping researchers stay on top of the new literature in this fast-moving and multifaceted field, fostering their creativity and productivity in bringing us ever closer to curing this deadly disease.
I'm a big fan of ACIR. I enjoy their weekly newsletters with clear, concise, and insightful summaries, complemented by excellent images. I've even used the images in some of my presentations to explain complex cancer immunotherapy findings. In our rapidly evolving field, their reliable and well-curated updates are invaluable.
Richard W. Vague Professor in Immunotherapy; Professor of PL&M; Director, Center for Cellular Immunotherapies; Director, Parker Institute for Cancer Immunotherapy; University of Pennsylvania Perelman School of Medicine. (Supporter since 2025).
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