Weekly Digests

2025

April

KEYSTONE SYMPOSIA: Cancer Immunotherapy: Clinical Lessons to New Modalities

April 9, 2025

The ACIR team attended the Keystone Symposia on Cancer Immunotherapy: Clinical Lessons to New Modalities held on March 16-19, 2025 in Banff, AB, Canada. This week’s extensive special feature covers select talks from the conference. We have organized the content by topics below. (This Keystone Symposia conference is available for On Demand viewing...

Translation dysregulation in cancer produces targetable antigens

April 2, 2025

Dysregulation of translation and protein synthesis is often observed in cancer, but whether this results in the production of targetable antigens has not been fully explored. Investigating this possibility, Weller, Bartok, and McGinnis et al. used CRISPR-Cas9 to study the effects of tRNA wybutosine (yW)-synthesizing protein 2 (TYW2) – a tRNA transferase that...

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